Takuma pernah menjadi pasien ayah Mayu yang merupakan seorang dokter. Takuma lahir dengan lubang di jantungnya. Takuma diberitahu bahwa ia tidak akan hidup lebih dari usia 20 tahun, kecuali ia menjalani transplantasi jantung.

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Kisahnya tentang penulis fiksi ilmiah, Sakutaro Makimura, yang menghabiskan waktunya untuk berkhayal dan menjalin hubungan yang damai dengan istrinya, Setsuko. Namun, ketika sang istri Setsuko didiagnosis menderita kanker usus dan diperkirakan waktu hidupnya hanya satu tahun, Sakutaro memutuskan untuk menulis satu cerita pendek untuk istrinya setiap hari setelah dokter memberitahunya bahwa tawa meningkatkan sistem kekebalan tubuh.

Di samping hubungan mereka yang semakin dekat, Nodame merasa ia dan Chiaki perlu fokus pada karir musik masing-masing.

Suatu hari, Keiko pergi bekerja dan meninggalkan anak-anaknya di apartemen dengan sedikit uang pegangan. Namun, ibu tunggal itu tidak kembali. Kebingungan karena sang ibu tak kunjung pulang, Akira berusaha mengurus ketiga adiknya sendiri dengan uang yang ditinggalkan oleh ibunya.

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Now his hair is so speedy that he can get a Solar burn up off!!!So for no less than two months I can't just take him out once the Sunshine is up((( and The natural way they didn't tell me above it, I were Blessed to satisfy An additional Canine proprietor who had the exact same concern ahead of. Terrible and unprofessional company!

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Pada peringatan satu tahun kematian sang istri, Takumi dan Yuji sedang berjalan-jalan di hutan ketika mereka bertemu dengan seorang wanita yang memiliki kemiripan dengan Mio.